Humasis

Tobacco smoke, which mainly causes lung cancer, contains a large amount of nicotine, which can cause dangerous acute toxicity disorders even at low concentrations.
Nicotine causes nausea, vomiting, diarrhea, headache, dizziness, nerve stimulation, hypertension, sweating, saliva secretion, etc., and when exposed to high concentrations of nicotine, it can cause convulsions and heart arrhythmia.

These nicotine are metabolized in the body and a metabolite called cotinine is produced, and cotinine is very stable in the body and has a half-life of about 17 hours.
Cortinine accumulated in the body, including nicotine e-cigarettes, is excreted in the urine for about 7 to 10 days, but it is detected up to 15 days due to individual differences such as smoking period and smoking method.